Structure of the Gene for Human Transglutaminase l *

Transglutaminase 1 (TG1) is an enzyme that is expressed and activated during terminal differentiation of keratinocytes and synthesizes cornified envelope by a cross-linking reaction. The gene encoding human T G l was isolated from human genomic DNA and eharacterized. It spans 14.3 kilobase pairs and is composed of 15 exons. All exon-intron junctional… CONTINUE READING