Structure of the GTPase-binding domain of Sec5 and elucidation of its Ral binding site.

@article{Mott2003StructureOT,
  title={Structure of the GTPase-binding domain of Sec5 and elucidation of its Ral binding site.},
  author={Helen R Mott and Daniel Nietlispach and Louise J Hopkins and Gladys Mirey and Jacques H. Camonis and Darerca Owen},
  journal={The Journal of biological chemistry},
  year={2003},
  volume={278 19},
  pages={17053-9}
}
The exocyst complex is involved in the final stages of exocytosis, when vesicles are targeted to the plasma membrane and dock. The regulation of exocytosis is vital for a number of processes, for example, cell polarity, embryogenesis, and neuronal growth formation. Regulation of the exocyst complex in mammals was recently shown to be dependent upon binding… CONTINUE READING