Structure of the 70S Ribosome Complexed with mRNA and tRNA

@article{Selmer2006StructureOT,
  title={Structure of the 70S Ribosome Complexed with mRNA and tRNA},
  author={M. Selmer and C. M. Dunham and F. Murphy and A. Weixlbaumer and Sabine Petry and A. Kelley and J. Weir and V. Ramakrishnan},
  journal={Science},
  year={2006},
  volume={313},
  pages={1935 - 1942}
}
The crystal structure of the bacterial 70S ribosome refined to 2.8 angstrom resolution reveals atomic details of its interactions with messenger RNA (mRNA) and transfer RNA (tRNA). A metal ion stabilizes a kink in the mRNA that demarcates the boundary between A and P sites, which is potentially important to prevent slippage of mRNA. Metal ions also stabilize the intersubunit interface. The interactions of E-site tRNA with the 50S subunit have both similarities and differences compared to those… Expand
Interactions of the ribosome with mRNA and tRNA.
Interaction of tRNA with Eukaryotic Ribosome
Intersubunit Bridges of the Bacterial Ribosome.
A structural understanding of the dynamic ribosome machine
  • T. Steitz
  • Biology, Medicine
  • Nature Reviews Molecular Cell Biology
  • 2008
The crystal structure of unmodified tRNAPhe from Escherichia coli
...
1
2
3
4
5
...

References

SHOWING 1-10 OF 105 REFERENCES
Structure of the 30S ribosomal subunit
Crystal Structure of the Ribosome at 5.5 Å Resolution
Identification of molecular interactions between P-site tRNA and the ribosome essential for translocation
  • J. Feinberg, S. Joseph
  • Biology, Medicine
  • Proceedings of the National Academy of Sciences of the United States of America
  • 2001
...
1
2
3
4
5
...