Structure of the 30S ribosomal subunit

@article{Wimberly2000StructureOT,
  title={Structure of the 30S ribosomal subunit},
  author={B. Wimberly and D. Brodersen and W. M. Clemons and R. Morgan-Warren and A. Carter and C. Vonrhein and T. Hartsch and V. Ramakrishnan},
  journal={Nature},
  year={2000},
  volume={407},
  pages={327-339}
}
  • B. Wimberly, D. Brodersen, +5 authors V. Ramakrishnan
  • Published 2000
  • Biology, Medicine
  • Nature
  • Genetic information encoded in messenger RNA is translated into protein by the ribosome, which is a large nucleoprotein complex comprising two subunits, denoted 30S and 50S in bacteria. Here we report the crystal structure of the 30S subunit from Thermus thermophilus, refined to 3 Å resolution. The final atomic model rationalizes over four decades of biochemical data on the ribosome, and provides a wealth of information about RNA and protein structure, protein–RNA interactions and ribosome… CONTINUE READING
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