Structure of mitochondrial transcription termination factor 3 reveals a novel nucleic acid-binding domain.

Abstract

In mammalian cells, a family of mitochondrial transcription termination factors (MTERFs) regulates mitochondrial gene expression. MTERF family members share a approximately 270 residues long MTERF-domain required for DNA binding and transcription regulation. However, the structure of this widely conserved domain is unknown. Here, we show that the MTERF… (More)
DOI: 10.1016/j.bbrc.2010.04.130

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