Structure of human adenovirus.

@article{Nemerow2012StructureOH,
  title={Structure of human adenovirus.},
  author={Glen R. Nemerow and Phoebe L. Stewart and V. Sivaprasad Reddy},
  journal={Current opinion in virology},
  year={2012},
  volume={2 2},
  pages={115-21}
}
A detailed structural analysis of the entire human adenovirus capsid has been stymied by the complexity and size of this 150 MDa macromolecular complex. Over the past 10 years, the steady improvements in viral genome manipulation concomitant with advances in crystallographic techniques and data processing software has allowed structure determination of this virus by X-ray diffraction at 3.5 Å resolution. The virus structure revealed the location, folds, and interactions of major and minor… CONTINUE READING