Structure of endogenous murine leukemia virus DNA in mouse genomes.

@article{Chattopadhyay1980StructureOE,
  title={Structure of endogenous murine leukemia virus DNA in mouse genomes.},
  author={Sisir Kanti Chattopadhyay and Marilyn R. Lander and Elaine Rands and Douglas R Lowy},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1980},
  volume={77 10},
  pages={
          5774-8
        }
}
By using molecularly cloned ecotropic AKR murine leukemia virus (MuLV) DNA, a 400-base-pair ecotropic type-specific segment in the env region has been identified. This DNA segment and other defined viral subgenomic fragments have been used as 32P-labeled probes to identify and analyze the structure of integrated ecotropic viral DNA sequences in uninfected mouse genomes. Those mice from which endogenous ecotropic MuLV of the AKR type have been isolated contained at least one virtually complete… CONTINUE READING
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