Structure of a molluscan cardioexcitatory neuropeptide.

@article{Price1977StructureOA,
  title={Structure of a molluscan cardioexcitatory neuropeptide.},
  author={D. Price and M. Greenberg},
  journal={Science},
  year={1977},
  volume={197 4304},
  pages={
          670-1
        }
}
A cardioexcitatory substance from ganglia of the clam Macrocallista nimbosa, formerly designated peak C, is the tetrapeptide amide Phe-Met-Arg-Phe-NH2. Its structure was determined by the combined use of Edman dansyl degradation and tryptic digestion. The structure was confirmed by synthesis. This neuropeptide is active at about 10(-8)M when assayed on molluscan muscle. 
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