Structure of a human common cold virus and functional relationship to other picornaviruses

@article{Rossmann1985StructureOA,
  title={Structure of a human common cold virus and functional relationship to other picornaviruses},
  author={Michael G. Rossmann and Eddy Arnold and John W. Erickson and Elizabeth A. Frankenberger and James P. Griffith and Hans J{\"u}rgen Hecht and John E. Johnson and Greg Kamer and Ming Luo and Anne G. Mosser and Roland R. Rueckert and Barbara Sherry and Gerrit Vriend},
  journal={Nature},
  year={1985},
  volume={317},
  pages={145-153}
}
We report the first atomic resolution structure of an animal virus, human rhinovirus 14. It is strikingly similar to known icosahedral plant RNA viruses. Four neutralizing immunogenic regions have been identified. These, and corresponding antigenic sequences of polio and foot-and-mouth disease viruses, reside on external protrusions. A large cleft on each icosahedral face is probably the host cell receptor binding site. 

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