Structure of a complex between a cap analogue and mRNA guanylyl transferase demonstrates the structural chemistry of RNA capping.

@article{Hkansson1998StructureOA,
  title={Structure of a complex between a cap analogue and mRNA guanylyl transferase demonstrates the structural chemistry of RNA capping.},
  author={Kjell H{\aa}kansson and Dale B. Wigley},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1998},
  volume={95 4},
  pages={
          1505-10
        }
}
Paramecium bursaria Chlorella virus PBCV-1 mRNA guanylyl transferase (capping enzyme) has been complexed with an mRNA cap analogue G[5']ppp[5']G and crystallized. The crystals belong to space group C2221 with unit cell dimensions a = 78.4 A, b = 164.1 A, c = 103.3 A, and diffraction data to 3.1 A has been collected by using synchrotron radiation. The structure has been solved by molecular replacement by using each of the two domains in the previously determined structure of the enzyme in… CONTINUE READING

Citations

Publications citing this paper.
SHOWING 1-10 OF 21 CITATIONS

References

Publications referenced by this paper.
SHOWING 1-3 OF 3 REFERENCES

Håkansson and Wigley Proc

  • 50 CCP4ActaCryst.D, 760–763. FIG. 4. A possible mechanism for formation of the Biochemistry
  • Natl. Acad. Sci. USA 95
  • 1998
2 Excerpts

Håkansson and Wigley Proc

  • S. J. Phillips, P. Eisenberg, P. George, Rutman, R. J. J. Biol. Chem. 240, 4393–4397. 1510 Biochemistry
  • Natl. Acad. Sci. USA 95
  • 1998

Similar Papers

Loading similar papers…