Structure of Vitamin B12: X-ray Crystallographic Evidence on the Structure of Vitamin B12
@article{Brink1954StructureOV, title={Structure of Vitamin B12: X-ray Crystallographic Evidence on the Structure of Vitamin B12}, author={C. Brink and Dorothy Mary Crowfoot Hodgkin and June Lindsey and Jenny Pickworth and John H. Robertson and JOHN G. White}, journal={Nature}, year={1954}, volume={174}, pages={1169-1171} }
58 Citations
Cobalt binding in the photosynthetic bacterium R. sphaeroides by X-ray absorption spectroscopy
- PhysicsBioMetals
- 2013
An X-ray absorption spectroscopy investigation was conducted on Rhodobacter sphaeroides cells to gain structural insights into the Co2+ binding to cellular components, suggesting the presence of carboxylate and sulfonate metal-binding functional groups, the latter arising from sulfolipids of the cell envelope.
Fragment-based ab initio phasing of peptidic nanocrystals by MicroED
- ChemistrybioRxiv
- 2021
ARCIMBOLDO, an automated, fragment-based approach to structure determination, expands the reach of MicroED to presently inaccessible peptidic structures including segments of human amyloids, and yeast and mammalian prions, and portends a more general phasing solution while limiting model bias for a wider set of chemical structures.
The drug discovery process: From ancient times to the present day
- BiologyBasic Principles of Drug Discovery and Development
- 2021
Cofactors and Coenzymes | Biosynthesis of Vitamin B12 (Cobalamin) and Related Corrinoids
- ChemistryEncyclopedia of Biological Chemistry III
- 2021
Notes of a protein crystallographer: the legacy of J.-B. J. Fourier – crystallography, time and beyond
- PhysicsActa crystallographica. Section D, Structural biology
- 2021
The legacy of J.-B. J. Fourier, a pioneer Egyptologist and premier mathematician and physicist of his time, in crystallography and many other scientific fields is reviewed in the context of nearly…
The requirement for cobalt in vitamin B12: A paradigm for protein metalation☆
- Biology, ChemistryBiochimica et biophysica acta. Molecular cell research
- 2020
Molecular Structure, Binding Affinity, and Biological Activity in the Epigenome
- Biology, ChemistryInternational journal of molecular sciences
- 2020
The present review is based on selected methodologies and applications supplying molecular structure, binding affinity and biological activity data for the development of new SARs in the context of proteins as epigenetic drug targets.
Crystallography of the past and in the future
- History
- 2020
ABSTRACT This paper is partly a summary of the book ‘From a grain of salt to the ribosome’ [1], with extension on some points. Sometimes the developments in science may be very rapid and not fully…
References
SHOWING 1-4 OF 4 REFERENCES
Beitrag zur Kenntnis der Vitamins B12. 1. Mitteilung
- Chemistry
- 1953
Vitamin B12 wurde in einem Gemisch von verdunnter Salzsaure und Butanol mit Wasserstoff und PtO2 hydriert, wobei unter den angegebenen Reaktionsbedingungen 5–6 Mol NH3 (pro Mol B12), β-Amino-propanol…
The chemistry of anti-pernicious anaemia factors. Part VI. The mode of combination of component alpha in vitamin B12.
- ChemistryThe Journal of pharmacy and pharmacology
- 1950