Structure of Some Crystalline Lysozyme-Inhibitor Complexes Determined by X-Ray Analysis At 6 Å Resolution
@article{Johnson1965StructureOS, title={Structure of Some Crystalline Lysozyme-Inhibitor Complexes Determined by X-Ray Analysis At 6 Å Resolution}, author={Louise N. Johnson and David C. Phillips}, journal={Nature}, year={1965}, volume={206}, pages={761-763} }
Structure of Some Crystalline Lysozyme-Inhibitor Complexes Determined by X-Ray Analysis At 6 A Resolution
191 Citations
Specificity of Cleavage of Chitotriose by Lysozyme
- Chemistry, BiologyNature
- 1967
The structure of lysozyme in the crystalline state is determined and chemical and kinetic approaches to the study of its mechanism of action in solution are investigated.
Proton Magnetic Resonance Studies of Human Lysozyme
- Chemistry, BiologyNature
- 1969
The high pK value of the single histidine residue of human lysozyme (7.1 at 32° C), together with thermodynamic data, indicate that this histidine is in a negatively charged environment and is…
Lysozymes characterized in Duck Egg-white: Isolation of a Histidine-less Lysozyme
- BiologyNature
- 1965
This work has purified, analysed and compared different lysozymes isolated from the duck egg-white, and found that they contain different properties that indicate their origins in the egg white of the duck.
Binding of N-acetylglucosamine to chicken egg lysozyme: a powder diffraction study
- Chemistry, Biology
- 2001
A binding mode for NAG was revealed which differed from that found in an earlier single-crystal study and probably represents a precursor trapped by rapid precipitation.
Localization of non-essential tryptophan residues for the biological activity of lysozyme.
- Chemistry, BiologyJournal of molecular biology
- 1967
High-Sensitivity Polarimetry and its Application to the Study of Small Conformational Changes in Proteins
- Chemistry, PhysicsNature
- 1966
High-Sensitivity Polarimetry and its Application to the Study of Small Conformational Changes in Proteins
Transport in Protein Crystals, Part I: Insights from Molecular Simulations
- ChemistryComputing in Science & Engineering
- 2007
In addition to simulations of transport processes in protein crystals, the importance of protein-solvent interactions is highlighted, for example, whether the catalytic properties of proteins are the same in crystal and in solution.
Mechanism and stereoelectronic effects in the lysozyme reaction.
- ChemistryCRC critical reviews in biochemistry
- 1987
Lysozyme occupies a special place in the history of enzymology as the first enzyme to have its three-dimensional crystal structure elucidated by Phillips and co-workers in 1965, but discussion of the conformational question came to a head only very recently with the suggestion that the fundamental stereoelectronic requirements of the glycoside-cleavage reaction might be decisive.
Structures of triclinic mono- and di-N-acetylglucosamine: lysozyme complexes--a crystallographic study.
- ChemistryJournal of molecular biology
- 1976
On the inhibition of hen egg-white lysozyme activity by aminoglycosidic antibiotics.
- Chemistry, BiologyBiochemical and biophysical research communications
- 1977
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