Structure of RizA, an L-amino-acid ligase from Bacillus subtilis.

Abstract

RizA is an L-amino-acid ligase from Bacillus subtilis that participates in the biosynthesis of rhizocticin, an oligopeptide antibiotic. The substrate-free form of RizA has been crystallized and the structure was solved at 2.8 Å resolution. The amino-acid-binding site appears to be capable of accommodating multiple amino acids, consistent with previous biochemical studies.

DOI: 10.1107/S2053230X15012698

Cite this paper

@article{Kagawa2015StructureOR, title={Structure of RizA, an L-amino-acid ligase from Bacillus subtilis.}, author={Wataru Kagawa and Toshinobu Arai and Shun Ishikura and Kuniki Kino and Hitoshi Kurumizaka}, journal={Acta crystallographica. Section F, Structural biology communications}, year={2015}, volume={71 Pt 9}, pages={1125-30} }