Structure of Hen Egg-White Lysozyme: A Three-dimensional Fourier Synthesis at 2 Å Resolution

@article{Blake1965StructureOH,
  title={Structure of Hen Egg-White Lysozyme: A Three-dimensional Fourier Synthesis at 2 Å Resolution},
  author={Colin C. F. Blake and D. F. Koenig and Gerald Mair and A. C. North and David C. Phillips and V. R. Sarma},
  journal={Nature},
  year={1965},
  volume={206},
  pages={757-761}
}
Structure of Hen Egg-White Lysozyme: A Three-dimensional Fourier Synthesis at 2 A Resolution 
Differences between the chemical structures of duck and hen egg-white lysozymes.
Histidine-free duck egg-white lysozyme III and hen egg-white lysozyme have similar but not identical structures.
Structural basis of antigen recognition: crystal structure of duck egg lysozyme
Lysozyme isoforms purified from duck eggs have been characterized by crystallography, mass spectrometry and their capacity to bind landmark antibodies.
The active site of hen egg-white lysozyme: flexibility and chemical bonding
Chemical bonding at the active site of lysozyme is analyzed on the basis of a multipole model employing transferable multipole parameters from a database. Large B factors at low temperatures reflect
Three-dimensional structure of thermolysin.
The electron density map of thermolysin indicates how the polypeptide chain is displaced throughout the overall shape of the molecule.
The lysozyme mechanism sorted — after 50 years
  • A. J. Kirby
  • Chemistry, Biology
    Nature Structural Biology
  • 2001
Unambiguous evidence for a glycosyl-enzyme intermediate on the lysozyme reaction pathway has recently been reported, finally settling what kind of mechanism this textbook enzyme uses.
Crystallization, structure solution and refinement of hen egg-white lysozyme at pH 8.0 in the presence of MPD.
Hen egg-white lysozyme has been crystallized at slightly alkaline pH using 2-methyl-2,4-pentanediol (MPD) as the precipitant. The crystals are nearly isomorphous to crystals grown at acidic pH using
Quantum Mechanics/Molecular Mechanics Simulations Show Saccharide Distortion is Required for Reaction in Hen Egg-White Lysozyme.
Hybrid quantum mechanics/molecular mechanics (QM/MM) calculations on lysozyme show significant distortion of the bound saccharide is required to facilitate the catalytic reaction.
Investigation of protein structure by means of 19F-NMR. A study of hen egg-white lysozyme.
TLDR
A comparison of the circular dichroic spectra and the activity towards Micrococcus lysodeikticus of both LF6 and native lysozyme reveals that the labeling causes no major conformational changes of the polypeptide backbone.
Three-dimensional Fourier Synthesis of Tosyl-elastase at 3.5 Å Resolution
X-ray diffraction data have been collected from four isomorphous crystalline derivatives of the proteolytic enzyme elastase, and a map of the three-dimensional electron density of the tosyl
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Structure Of Lysozyme: A Fourier Map of the Electron Density at 6 A Resolution obtained by X-ray Diffraction
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