Structure of Functionally Activated Small Ribosomal Subunit at 3.3 Å Resolution

@article{Schluenzen2000StructureOF,
  title={Structure of Functionally Activated Small Ribosomal Subunit at 3.3 {\AA} Resolution},
  author={F. Schluenzen and A. Tocilj and R. Zarivach and J. Harms and M. Gluehmann and D. Janell and A. Bashan and H. Bartels and I. Agmon and F. Franceschi and A. Yonath},
  journal={Cell},
  year={2000},
  volume={102},
  pages={615-623}
}
The small ribosomal subunit performs the decoding of genetic information during translation. The structure of that from Thermus thermophilus shows that the decoding center, which positions mRNA and three tRNAs, is constructed entirely of RNA. The entrance to the mRNA channel will encircle the message when a latch-like contact closes and contributes to processivity and fidelity. Extended RNA helical elements that run longitudinally through the body transmit structural changes, correlating events… Expand

Figures and Tables from this paper

Meanderings of the mRNA through the ribosome.
On Ribosome Conservation and Evolution
Symmetry at the active site of the ribosome: structural and functional implications
High Resolution Structure of the Large Ribosomal Subunit from a Mesophilic Eubacterium
Correlating ribosome function with high-resolution structures.
A structural view of translation initiation in bacteria
...
1
2
3
4
5
...

References

SHOWING 1-10 OF 167 REFERENCES
Solution Structure of the E. coli 70S Ribosome at 11.5 Å Resolution
A ratchet-like inter-subunit reorganization of the ribosome during translocation
Crystal structure of the S15–rRNA complex
A functional pseudoknot in 16S ribosomal RNA.
Ribosomes and translation.
...
1
2
3
4
5
...