Structure of Colchicine

@article{Dewar1945StructureOC,
  title={Structure of Colchicine},
  author={M. Dewar},
  journal={Nature},
  year={1945},
  volume={155},
  pages={141-142}
}
IN view of the remarkable physiological properties of colchicine its chemical nature is of some interest. Until recently, the structure (I) proposed by Windaus1 has been generally accepted, although the stability of colchicine did not suggest a 9-amino-9: 10-di-hydrophenanthrene system, and although the salicylaldehyde enol structure of ring C appeared fantastic. Cohen, Cook and Roe2 have now provided evidence that ring B must be 7-membered, but the exact location of the acetamido group remains… Expand
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References

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Structure of Stipitatic Acid
Birkinshaw, Chambers and Raistrick1 have described stipitatic acid, a metabolite of the mould Penicillium stipitatum, to which, after lengthy examination, they could ascribe no reasonable structure.Expand