Structure of Acid phosphatases.

  title={Structure of Acid phosphatases.},
  author={C{\'e}sar L. Araujo and Pirkko T. Vihko},
  journal={Methods in molecular biology},
Acid phosphatases are enzymes that have been studied extensively due to the fact that their dysregulation is associated with pathophysiological conditions. This characteristic has been exploited for the development of diagnostic and therapeutic methods. As an example, prostatic acid phosphatase was the first marker for metastatic prostate cancer diagnosis and the dysregulation of tartrate resistant acid phosphatase is associated with abnormal bone resorption linked to osteoporosis. The… CONTINUE READING