Structure of 20S proteasome from yeast at 2.4Å resolution

@article{Groll1997StructureO2,
  title={Structure of 20S proteasome from yeast at 2.4{\AA} resolution},
  author={Michael Groll and Lars Ditzel and Jan L{\"o}we and Daniela Stock and Matthias Bochtler and Hans D. Bartunik and Robert Huber},
  journal={Nature},
  year={1997},
  volume={386},
  pages={463-471}
}
The crystal structure of the 20S proteasome from the yeast Saccharomyces cerevisiae shows that its 28 protein subunits are arranged as an (α1...α7, β1...β7)2 complex in four stacked rings and occupy unique locations. The interior of the particle, which harbours the active sites, is only accessible by some very narrow side entrances. The β-type subunits are synthesized as proproteins before being proteolytically processed for assembly into the particle. The proforms of three of the seven… CONTINUE READING
BETA

Topics from this paper.

Citations

Publications citing this paper.
SHOWING 1-10 OF 720 CITATIONS, ESTIMATED 58% COVERAGE

Prokaryotic proteasomes: nanocompartments of degradation.

  • Journal of molecular microbiology and biotechnology
  • 2013
VIEW 6 EXCERPTS
CITES BACKGROUND
HIGHLY INFLUENCED

The proteasome: molecular machinery and pathophysiological roles.

VIEW 13 EXCERPTS
CITES BACKGROUND
HIGHLY INFLUENCED

Keepers at the final gates: regulatory complexes and gating of the proteasome channel.

  • Cellular and molecular life sciences : CMLS
  • 2004
VIEW 10 EXCERPTS
CITES BACKGROUND
HIGHLY INFLUENCED

The Y. bercovieri Anbu crystal structure sheds light on the evolution of highly (pseudo)symmetric multimers

  • Journal of molecular biology
  • 2017
VIEW 7 EXCERPTS
CITES BACKGROUND & METHODS
HIGHLY INFLUENCED

Prediction of cleavage fragments generated by the proteasome

VIEW 4 EXCERPTS
CITES BACKGROUND
HIGHLY INFLUENCED

In Silico Strategies to Modulate DNA Damage Response

VIEW 8 EXCERPTS
CITES BACKGROUND & METHODS
HIGHLY INFLUENCED

FILTER CITATIONS BY YEAR

1997
2019

CITATION STATISTICS

  • 64 Highly Influenced Citations

  • Averaged 21 Citations per year from 2017 through 2019

Similar Papers

Loading similar papers…