Structure-function relationship of the TRP channel superfamily.

  title={Structure-function relationship of the TRP channel superfamily.},
  author={Grzegorz Owsianik and Dieter D'hoedt and Thomas Voets and Bernd Nilius},
  journal={Reviews of physiology, biochemistry and pharmacology},
Transient receptor potential (TRP) channels are involved in the perception of a wide range of physical and chemical stimuli, including temperature and osmolarity changes, light, pain, touch, taste and pheromones, and in the initiation of cellular responses thereupon. Since the last decade, rapid progress has been made in the identification and characterization of new members of the TRP superfamily. They constitute a large superfamily of cation channels that are expressed in almost all cell… CONTINUE READING