Structure-function analysis of HKE4, a member of the new LIV-1 subfamily of zinc transporters.

  title={Structure-function analysis of HKE4, a member of the new LIV-1 subfamily of zinc transporters.},
  author={Kathryn M Taylor and Helen E Morgan and Andrea Butts Johnson and Robert Ian Nicholson},
  journal={The Biochemical journal},
  volume={377 Pt 1},
The KE4 proteins are an emerging group of proteins with little known functional data. In the present study, we report the first characterization of the recombinant human KE4 protein in mammalian cells. The KE4 sequences are included in the subfamily of ZIP (Zrt-, Irt-like Proteins) zinc transporters, which we have termed LZT (LIV-1 subfamily of ZIP zinc Transporters). All these LZT sequences contain similarities to ZIP transporters, including the consensus sequence in transmembrane domain IV… CONTINUE READING


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