Structure determination of grandifotane A from Khaya grandifoliola by NMR, X-ray diffraction, and ECD calculation.

  title={Structure determination of grandifotane A from Khaya grandifoliola by NMR, X-ray diffraction, and ECD calculation.},
  author={Tao Yuan and Rongxiu Zhu and Hua Zhang and Oluwatoyin Odeku and Sheng-ping Yang and Shang-gao Liao and Jian‐Min Yue},
  journal={Organic letters},
  volume={12 2},
Grandifotane A (1), a limonoid with an unprecedented carbon skeleton, was isolated from the stem bark of Khaya grandifoliola. The structure of 1 with the absolute configuration was determined by spectroscopic data, X-ray crystallography, and ECD calculation. A biogenetic route for grandifotane A (1) involving an enzymatic Baeyer-Villiger oxidation as the key step is proposed. 

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