Structure binding relationship of galactosylated Glycoclusters toward Pseudomonas aeruginosa lectin LecA using a DNA-based carbohydrate microarray.

@article{Gerland2014StructureBR,
  title={Structure binding relationship of galactosylated Glycoclusters toward Pseudomonas aeruginosa lectin LecA using a DNA-based carbohydrate microarray.},
  author={B{\'e}atrice Gerland and Alice Goudot and Caroline Ligeour and Gwladys Pourceau and A. Y. Meyer and S{\'e}bastien Vidal and Thomas G{\'e}hin and Olivier Vidal and {\'E}liane Souteyrand and J L Vasseur and Yann Chevolot and François Morvan},
  journal={Bioconjugate chemistry},
  year={2014},
  volume={25 2},
  pages={379-92}
}
Pseudomonas aeruginosa (PA) is a major public health issue due to its impact on nosocomial infections as well as its impact on cystic fibrosis patient mortality. One of the main concerns is its ability to develop antibiotic resistance. Therefore, inhibition of PA virulence has been proposed as an alternative strategy to tackle PA based infections. LecA (or… CONTINUE READING