Structure-based analysis of VDAC1: N-terminus location, translocation, channel gating and association with anti-apoptotic proteins.

Abstract

Structural studies place the VDAC1 (voltage-dependent anion channel 1) N-terminal region within the channel pore. Biochemical and functional studies, however, reveal that the N-terminal domain is cytoplasmically exposed. In the present study, the location and translocation of the VDAC1 N-terminal domain, and its role in voltage-gating and as a target for… (More)
DOI: 10.1042/BJ20112079

Topics

7 Figures and Tables

Statistics

02040602012201320142015201620172018
Citations per Year

168 Citations

Semantic Scholar estimates that this publication has 168 citations based on the available data.

See our FAQ for additional information.

Slides referencing similar topics