Structure-based Ligand Design and the Promise Held for Antiprotozoan Drug Discovery*

Abstract

The development of the pharmaceutical industry, driven by progress in chemistry, biology, and technology, ranks as one of the most successful of human endeavors. However, serious health problems persist, among which are diseases caused by protozoan parasites, largely ignored in modern times. Advances in genomic sciences, molecular and structural biology… (More)
DOI: 10.1074/jbc.R800072200

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