Structure and trafficking of NMDA and GABAA receptors.

@article{Stephenson2006StructureAT,
  title={Structure and trafficking of NMDA and GABAA receptors.},
  author={F Anne Stephenson},
  journal={Biochemical Society transactions},
  year={2006},
  volume={34 Pt 5},
  pages={
          877-81
        }
}
  • F. Stephenson
  • Published 1 October 2006
  • Biology
  • Biochemical Society transactions
The fidelity of synaptic function is dependent on the expression of the appropriate neurotransmitter receptor subtype, the targeting and trafficking of receptors to synapses as well as the regulation of the actual number of receptors at synapses. GABAA (gamma-aminobutyric acid type A) receptors and NMDA (N-methyl-D-aspartate) receptors are both examples of ligand-gated, heteromeric neurotransmitter receptors whose cell-surface expression is dynamic and tightly regulated. NMDA receptors are… 

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