Structure and sequence of mutations induced by ionizing radiation at selectable loci in Chinese hamster ovary cells.

Abstract

The spectrum of mutations induced by ionizing radiation at two non-essential genetic loci varies markedly. Those at the adenine phosphoribosyl transferase (aprt) locus predominantly have no detectable alterations of gene structure on Southern blots, while those at the hypoxanthine guanine phosphoribosyl transferase (hprt) locus are largely massive deletions… (More)

Topics

  • Presentations referencing similar topics