Structure and sequence analysis of influenza A virus nucleoprotein

@article{Ng2009StructureAS,
  title={Structure and sequence analysis of influenza A virus nucleoprotein},
  author={Andy Ka-Leung Ng and Jia-huai Wang and Pang-Chui Shaw},
  journal={Science in China Series C: Life Sciences},
  year={2009},
  volume={52},
  pages={439-449}
}
Influenza A virus nucleoprotein (NP) forms homo-oligomers and multiple copies of NP wrap around genomic RNA, along with a trimeric polymerase making up ribonucleoprotein (RNP) complex. Sequence comparison of more than 2500 influenza A NP showed that this protein contains 30.1 % of polymorphic residues. NP is composed of a head and a body domain and a tail loop/ linker region. The head domain is more conserved than the body domain, as revealed from the structure-based sequence alignment. NP… 
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