Structure and metabolism of peptidoglycan and molecular requirements allowing its detection by the Drosophila innate immune system.

@article{MenginLecreulx2005StructureAM,
  title={Structure and metabolism of peptidoglycan and molecular requirements allowing its detection by the Drosophila innate immune system.},
  author={Dominique Mengin-Lecreulx and Bruno Lema{\^i}tre},
  journal={Journal of endotoxin research},
  year={2005},
  volume={11 2},
  pages={
          105-11
        }
}
Peptidoglycan (murein) is a major essential and specific constituent of the bacterial cell wall. Its main function is to protect cells against the internal osmotic pressure and to maintain the characteristic cell shape. It also serves as a platform for the anchoring of specific proteins and other cell wall components. This giant macromolecule is composed of long glycan chains cross-linked by short peptides. Any alteration of the disaccharide-peptide basic unit results in a global change of… CONTINUE READING

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