Structure and mechanism of the chalcogen-detoxifying protein TehB from Escherichia coli.

Abstract

The oxyanion derivatives of the chalcogens tellurium and selenium are toxic to living organisms even at very low levels. Bacteria have developed mechanisms to overcome their toxicity by methylating them. The structure of TehB from Escherichia coli has been determined in the presence of the cofactor analogues SAH (S-adenosylhomocysteine) and sinefungin (a… (More)
DOI: 10.1042/BJ20102014

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