Structure and mechanism of copper, zinc superoxide dismutase

@article{Tainer1983StructureAM,
  title={Structure and mechanism of copper, zinc superoxide dismutase},
  author={John A. Tainer and Elizabeth D. Getzoff and Jane. S. Richardson and David C. Richardson},
  journal={Nature},
  year={1983},
  volume={306},
  pages={284-287}
}
Copper, zinc superoxide dismutase (SOD) catalyses the very rapid two-step dismutation of the toxic superoxide radical (O− 2) to molecular oxygen and hydrogen peroxide through the alternate reduction and oxidation of the active-site copper1. We report here that after refitting and further refinement of the previous 2 Å structure of SOD2, analysis of the new model and its calculated molecular surface shows an extensive surface topography of sequence-conserved residues stabilized by underlying… 
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