Structure and gating of the nuclear pore complex

  title={Structure and gating of the nuclear pore complex},
  author={Matthias Eibauer and Mauro Pellanda and Yagmur Turgay and Anna Dubrovsky and Annik Wild and Ohad Medalia},
  booktitle={Nature communications},
Nuclear pore complexes (NPCs) perforate the nuclear envelope and allow the exchange of macromolecules between the nucleus and the cytoplasm. To acquire a deeper understanding of this transport mechanism, we analyse the structure of the NPC scaffold and permeability barrier, by reconstructing the Xenopus laevis oocyte NPC from native nuclear envelopes up to 20 Å resolution by cryo-electron tomography in conjunction with subtomogram averaging. In addition to resolving individual protein domains… CONTINUE READING
Recent Discussions
This paper has been referenced on Twitter 1 time over the past 90 days. VIEW TWEETS

From This Paper

Topics from this paper.
32 Citations
10 References
Similar Papers


Publications citing this paper.
Showing 1-10 of 32 extracted citations


Publications referenced by this paper.
Showing 1-10 of 10 references

Structural basis for assembly and function of the Nup82 complex in the nuclear pore scaffold

  • M Gaik
  • J. Cell Biol
  • 2015

Similar Papers

Loading similar papers…