Structure and functional relationships of archaeal and eukaryal histones and nucleosomes

  title={Structure and functional relationships of archaeal and eukaryal histones and nucleosomes},
  author={K. Sandman and J. Reeve},
  journal={Archives of Microbiology},
  • K. Sandman, J. Reeve
  • Published 2000
  • Biology, Medicine
  • Archives of Microbiology
  • Abstract. A decade after the discovery of histones in Archaea, there is now also a biochemical description of the archaeal nucleosome. A tetrameric core of archaeal histones is encircled by ~80 bp of DNA, and nuclease digestions indicate that adjacent archaeal nucleosomes exist in vivo compacting archaeal genomic DNA. Most Eukarya employ a similar structure to organize their chromosomal DNA, the eukaryal nucleosome, with a histone octamer and 146 bp of DNA. Here we compare the properties of… CONTINUE READING
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