Structure and functional relationships of archaeal and eukaryal histones and nucleosomes

@article{Sandman2000StructureAF,
  title={Structure and functional relationships of archaeal and eukaryal histones and nucleosomes},
  author={Kathleen Sandman and John N. Reeve},
  journal={Archives of Microbiology},
  year={2000},
  volume={173},
  pages={165-169}
}
Abstract. A decade after the discovery of histones in Archaea, there is now also a biochemical description of the archaeal nucleosome. A tetrameric core of archaeal histones is encircled by ~80 bp of DNA, and nuclease digestions indicate that adjacent archaeal nucleosomes exist in vivo compacting archaeal genomic DNA. Most Eukarya employ a similar structure to organize their chromosomal DNA, the eukaryal nucleosome, with a histone octamer and 146 bp of DNA. Here we compare the properties of… 
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Molecular components of the archaeal nucleosome.
Histones predate the split between bacteria and archaea
TLDR
The detection and classification of two new groups of histone homologs are reported, which are present in both archaea and bacteria and resemble eukaryotic core histone subunits and show sequence patterns characteristic of DNA binding.
Both DNA and Histone Fold Sequences Contribute to Archaeal Nucleosome Stability*
TLDR
If differences in this interface do result in archaeal histone cores with different sequence preferences, then the assembly of alternativearchaeal nucleosome tetramer cores could provide an unanticipated and novel structural mechanism to regulate gene expression.
Chromatin Polymorphism and the Nucleosome Superfamily: A Genealogy
TLDR
Nucleosomes were discovered more than thirty years ago as the basic repeating units of chromatin and have progressively revealed their taste to come in many appearances, upon either adjunction of other proteins, histone substitution for isoforms (histone variants), depletion of one or the two H2A-H2B dimers (sub-nucleosome), intimate two-particle association, or isomeric structural alterations.
Nanoarchaeal Origin of Histone H3?
TLDR
The properties of NEQ288 suggest an intermediate between the archaeal and H3 histone lineages and an evolutionary step toward the now-mandatory assembly of eukaryotic histones into heterodimers.
An Archaeal Histone Is Required for Transformation of Thermococcus kodakarensis
TLDR
The construction and properties of T. kodakarensis strains that have TK1413 or TK2289 deleted, the genes that encode HTkA and HTkB, respectively, the two archaeal histones present in this archaeon are reported.
Structure of Alba: an archaeal chromatin protein modulated by acetylation
TLDR
A model for the Alba–DNA interaction is presented consistent with the available structural, biophysical and electron microscopy data.
Extended Archaeal Histone-Based Chromatin Structure Regulates Global Gene Expression in Thermococcus kodakarensis
TLDR
Global transcriptome changes resultant from varying chromatin landscapes reveal the regulatory importance of higher-order histone-based chromatin architectures in regulating archaeal gene expression.
Physical and functional interaction of the archaeal single-stranded DNA-binding protein SSB with RNA polymerase.
TLDR
The potential for promoter melting by SSB is demonstrated, suggesting a plausible basis for the stimulation of transcription and revealing an unexpected role for single-stranded DNA-binding proteins in transcription in archaea.
Archeal DNA replication: eukaryal proteins in a bacterial context.
TLDR
In this review the current knowledge of the mechanisms governing DNA replication in archaea is summarized and the similarities and differences of those of bacteria and eukarya are highlighted.
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