• DOI:10.1007/s002039900122
Corpus ID: 28946064

Structure and functional relationships of archaeal and eukaryal histones and nucleosomes

@article{Sandman2000StructureAF,
  title={Structure and functional relationships of archaeal and eukaryal histones and nucleosomes},
  author={K. Sandman and J. Reeve},
  journal={Archives of Microbiology},
  year={2000},
  volume={173},
  pages={165-169}
}

K. Sandman, J. Reeve

Published 2000

Biology, Medicine

Archives of Microbiology

Abstract. A decade after the discovery of histones in Archaea, there is now also a biochemical description of the archaeal nucleosome. A tetrameric core of archaeal histones is encircled by ~80 bp of DNA, and nuclease digestions indicate that adjacent archaeal nucleosomes exist in vivo compacting archaeal genomic DNA. Most Eukarya employ a similar structure to organize their chromosomal DNA, the eukaryal nucleosome, with a histone octamer and 146 bp of DNA. Here we compare the properties of… CONTINUE READING

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