Structure and functional analysis of a marine bacterial carotenoid biosynthesis gene cluster and astaxanthin biosynthetic pathway proposed at the gene level

@article{Misawa1995StructureAF,
  title={Structure and functional analysis of a marine bacterial carotenoid biosynthesis gene cluster and astaxanthin biosynthetic pathway proposed at the gene level},
  author={Norihiko Misawa and Yoshinori Satomi and Keiji Kondo and Akihiro Yokoyama and Susumu Kajiwara and T. Saito and Takeshi Ohtani and Wataru Miki},
  journal={Journal of Bacteriology},
  year={1995},
  volume={177},
  pages={6575 - 6584}
}
A carotenoid biosynthesis gene cluster for the production of astaxanthin was isolated from the marine bacterium Agrobacterium aurantiacum. This cluster contained five carotenogenic genes with the same orientation, which were designated crtW, crtZ, crtY, crtI, and crtB. The stop codons of individual crt genes except for crtB overlapped the start codons of the following crt genes. Escherichia coli transformants carrying the Erwinia uredovora carotenoid biosynthesis genes provide suitable… 
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TLDR
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TLDR
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