Structure and function of the spleen

@article{Mebius2005StructureAF,
  title={Structure and function of the spleen},
  author={Reina E Mebius and Georg Kraal},
  journal={Nature Reviews Immunology},
  year={2005},
  volume={5},
  pages={606-616}
}
The spleen combines the innate and adaptive immune system in a uniquely organized way. The structure of the spleen enables it to remove older erythrocytes from the circulation and leads to the efficient removal of blood-borne microorganisms and cellular debris. This function, in combination with a highly organized lymphoid compartment, makes the spleen the most important organ for antibacterial and antifungal immune reactivity. A better understanding of the function of this complex organ has… Expand

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