Structure and function of the extracellular calcium-sensing receptor (Review).

  • M Bai
  • Published 1999 in International journal of molecular medicine


The extracellular calcium-sensing receptor (CaR) originally cloned from bovine parathyroid gland is a G protein-coupled receptor. The physiological relevance of the cloned CaR for sensing and regulating the extracellular calcium concentration has been established by identifying hyper- and hypocalcemic disorders resulting from inactivating and activating… (More)