Structure and function of the cytoskeleton of a Dictyostelium myosin- defective mutant

@article{Fukui1990StructureAF,
  title={Structure and function of the cytoskeleton of a Dictyostelium myosin- defective mutant},
  author={Yoshio Fukui and Arturo De Lozanne and James A Spudich},
  journal={The Journal of Cell Biology},
  year={1990},
  volume={110},
  pages={367 - 378}
}
To study the role of conventional myosin in nonmuscle cells, we determined the cytoskeletal organization and physiological responses of a Dictyostelium myosin-defective mutant. Dictyostelium hmm cells were created by insertional mutagenesis of the myosin heavy chain gene (De Lozanne, A., and J. A. Spudich. 1987. Science (Wash. DC). 236: 1086-1091). Western… CONTINUE READING