Structure and function of specialized cilia in the exocrine pancreas.

Abstract

Cilia are found in acinar and ductular lumina. Most descriptions of human or dog pancreatic tissue have indicated that these are probably motile structures which move and/or mix pancreatic secretion. A recent study interpreted arrangements of microtubules within cilia which deviated from the classic 9 + 2 pattern as indicating pathological change. There have been suggestions, however, from studies on nonmammalian and human pancreas, that the structure of pancreatic cilia suggests a sensory function. The present paper reports studies on the ultrastructural organization of the specialized cilia in human and canine pancreatic tissue. The pattern of microtubular organization resembles that of cilia modified for chemoreception rather than that of classic kinocilia. It is concluded that pancreatic ductular cilia are sensory rather than motile, providing a mechanism for monitoring general or specific molecular concentrations.

Cite this paper

@article{Bockman1986StructureAF, title={Structure and function of specialized cilia in the exocrine pancreas.}, author={Dale E. Bockman and Markus W. B{\"{u}chler and Hans G{\"{u}nter Beger}, journal={International journal of pancreatology : official journal of the International Association of Pancreatology}, year={1986}, volume={1 1}, pages={21-8} }