Structure and function of WD40 domain proteins

  title={Structure and function of WD40 domain proteins},
  author={Chao Xu and Jinrong Min},
  journal={Protein & Cell},
The WD40 domain exhibits a β-propeller architecture, often comprising seven blades. The WD40 domain is one of the most abundant domains and also among the top interacting domains in eukaryotic genomes. In this review, we will discuss the identification, definition and architecture of the WD40 domains. WD40 domain proteins are involved in a large variety of cellular processes, in which WD40 domains function as a protein-protein or protein-DNA interaction platform. WD40 domain mediates molecular… CONTINUE READING