Structure and function of Na(+)-symporters with inverted repeats.

  title={Structure and function of Na(+)-symporters with inverted repeats.},
  author={Jeff Abramson and Ernest M Wright},
  journal={Current opinion in structural biology},
  volume={19 4},
Symporters are membrane proteins that couple energy stored in electrochemical potential gradients to drive the cotransport of molecules and ions into cells. Traditionally, proteins are classified into gene families based on sequence homology and functional properties, for example the sodium glucose (SLC5 or Sodium Solute Symporter Family, SSS or SSF) and GABA (SLC6 or Neurotransmitter Sodium Symporter Family, NSS or SNF) symporter families [1-4]. Recently, it has been established that four Na… CONTINUE READING

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