Structure and function insights into the NuRD chromatin remodeling complex

@article{Torchy2015StructureAF,
  title={Structure and function insights into the NuRD chromatin remodeling complex},
  author={Morgan P. Torchy and Ali Hamiche and Bruno P. Klaholz},
  journal={Cellular and Molecular Life Sciences},
  year={2015},
  volume={72},
  pages={2491-2507}
}
Transcription regulation through chromatin compaction and decompaction is regulated through various chromatin-remodeling complexes such as nucleosome remodeling and histone deacetylation (NuRD) complex. NuRD is a 1 MDa multi-subunit protein complex which comprises many different subunits, among which histone deacetylases HDAC1/2, ATP-dependent remodeling enzymes CHD3/4, histone chaperones RbAp46/48, CpG-binding proteins MBD2/3, the GATAD2a (p66α) and/or GATAD2b (p66β) and specific DNA-binding… CONTINUE READING
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