Structure and expression of the rat inositol 1,4,5-trisphosphate receptor.

@article{Mignery1990StructureAE,
  title={Structure and expression of the rat inositol 1,4,5-trisphosphate receptor.},
  author={Gregory A. Mignery and Christopher L Newton and B T Archer and Thomas C S{\"u}dhof},
  journal={The Journal of biological chemistry},
  year={1990},
  volume={265 21},
  pages={12679-85}
}
The complete primary structure of the inositol 1,4,5-trisphosphate receptor from rat brain was elucidated using a series of overlapping cDNA clones. Two different sets of clones that either contain or lack a 45-nucleotide sequence in the amino-terminal third of the protein were isolated, suggesting a differential splicing event that results in the… CONTINUE READING