Structure and expression of the human oocyte-specific histone H1 gene elucidated by direct RT-nested PCR of a single oocyte.

@article{Tanaka2003StructureAE,
  title={Structure and expression of the human oocyte-specific histone H1 gene elucidated by direct RT-nested PCR of a single oocyte.},
  author={Yudai Tanaka and Shingo Kato and Mamoru Tanaka and Naoaki Kuji and Yasunori Yoshimura},
  journal={Biochemical and biophysical research communications},
  year={2003},
  volume={304 2},
  pages={
          351-7
        }
}
Oocyte-specific histone H1 is expressed during oogenesis and early embryogenesis. It has been described in mice and some nonmammalian species, but not in humans. Here, we identified the cDNA in unfertilized human oocytes using direct RT-nested PCR of a single cell. Sequencing of this cDNA indicated an open reading frame encoding a 347-amino acid protein. Expression was oocyte-specific. Homology was closest with the corresponding gene of mouse (H1oo; 42.3%), and, to lesser extent, with that of… CONTINUE READING
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Mechanism of action of disease modifying anti - rheumatic agent , gold sodium thiomalate ( GSTM )

  • A. Aggarwal Mangalam, S. Naik
  • Int . Immunopharmacol .
  • 2001

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