Structure and expression of the herpes simplex virus type 2 glycoprotein gB gene.

@article{Stuv1987StructureAE,
  title={Structure and expression of the herpes simplex virus type 2 glycoprotein gB gene.},
  author={L L Stuv{\'e} and Sheryl Brown-Shimer and C A Pachl and R. C. Najarian and Dino Dina and Rae Lynn Burke},
  journal={Journal of virology},
  year={1987},
  volume={61 2},
  pages={326-35}
}
The gene for glycoprotein gB2 of herpes simplex virus type 2 strain 333 was cloned, sequenced, and expressed in mammalian cells. The gB2 protein had an overall nucleotide and amino acid sequence homology of 86% with the cognate gB1 protein. However, of the 125 amino acid substitutions or deletions, only 12.5% were conservative replacements. These… CONTINUE READING