Structure and expression of fibrillin-2, a novel microfibrillar component preferentially located in elastic matrices

@article{Zhang1994StructureAE,
  title={Structure and expression of fibrillin-2, a novel microfibrillar component preferentially located in elastic matrices},
  author={Hailan Zhang Hailan Zhang and Stephen D Apfelroth and Wei-xin Hu and E. Christine Davis and Carlos. Massa Sanguineti and Jeffrey Bonadio and Robert P. Mecham and Fernando Rivadeneira Ramirez},
  journal={The Journal of Cell Biology},
  year={1994},
  volume={124},
  pages={855 - 863}
}
During the previous cloning of the fibrillin gene (FBN1), we isolated a partial cDNA coding for a fibrillin-like peptide and mapped the corresponding gene (FBN2) to human chromosome 5. (Lee, B., M. Godfrey, E. Vitale, H. Hori, M. G. Mattei, M. Sarfarazi, P. Tsipouras, F. Ramirez, and D. W. Hollister. 1991. Nature [Lond.]. 352:330-334). The study left, however, unresolved whether or not the FBN2 gene product is an extracellular component structurally related to fibrillin. Work presented in this… CONTINUE READING

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