Structure and expression of conserved Wnt pathway components in the demosponge Amphimedon queenslandica

@article{Adamska2010StructureAE,
  title={Structure and expression of conserved Wnt pathway components in the demosponge Amphimedon queenslandica},
  author={M. Adamska and C. Larroux and M. Adamski and K. Green and E. Lovas and D. Koop and G. Richards and C. Zwafink and B. Degnan},
  journal={Evolution \& Development},
  year={2010},
  volume={12}
}
SUMMARY Wnt‐signalling plays a critical role in animal development, and its misregulation results in serious human diseases, including cancer. While the Wnt pathway is well studied in eumetazoan models, little is known about the evolutionary origin of its components and their functions. Here, we have identified key machinery of the Wnt–β‐catenin (canonical)‐signalling pathway that is encoded in the Amphimedon queenslandica (Demospongiae; Porifera) genome, namely Wnt, Fzd, SFRP, Lrp5/6, Dvl… Expand
Surprisingly rich repertoire of Wnt genes in the demosponge Halisarca dujardini
[Wnt signaling pathway and the Evo-Devo of deuterostome axis].
Characterization of the Wnt signalling system in the coral Acropora millepora
Evolutionary dynamics of the Wnt gene family: implications for lophotrochozoans
Developmental Signalling and Emergence of Animal Multicellularity
Insights into Frizzled evolution and new perspectives
...
1
2
3
4
5
...

References

SHOWING 1-10 OF 152 REFERENCES
Wnt and TGF-β Expression in the Sponge Amphimedon queenslandica and the Origin of Metazoan Embryonic Patterning
Isolation and characterization of Wnt pathway‐related genes from Porifera
Two Oppositely Localised Frizzled RNAs as Axis Determinants in a Cnidarian Embryo
The dawn of developmental signaling in the metazoa.
A WNT of things to come: evolution of Wnt signaling and polarity in cnidarians.
The Amphimedon queenslandica genome and the evolution of animal complexity
Early evolution of animal cell signaling and adhesion genes
...
1
2
3
4
5
...