Structure and expression of Xenopus tropicalisBMP-2 and BMP-4 genes

  title={Structure and expression of Xenopus tropicalisBMP-2 and BMP-4 genes},
  author={S. Kn{\"o}chel and K. Dillinger and M. K{\"o}ster and W. Knöchel},
  journal={Mechanisms of Development},
  • S. Knöchel, K. Dillinger, +1 author W. Knöchel
  • Published 2001
  • Medicine, Biology
  • Mechanisms of Development
  • The Xenopus tropicalis BMP-2 and BMP-4 genes have been cloned and sequenced. A comparison with the corresponding genes from X. laevis reveals that the BMP-4 genes are conserved at a higher extent than the BMP-2 genes. This is especially evident for the intron sequences, but is also reflected by the exon sequences. While the amino acids of X. tropicalis and X. laevis BMP-4 proteins diverge at about 4%, those of BMP-2 proteins diverge at about 7%. By reverse transcriptase polymerase chain… CONTINUE READING
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