Structure and evolution of the extended B7 family.

  title={Structure and evolution of the extended B7 family.},
  author={J. P. Henry and Marcia Madsen Miller and Pierre Pontarotti},
  journal={Immunology today},
  volume={20 6},
Here, Joëlle Henry and colleagues explore structural and evolutionary relationships between the B7 costimulator molecules and a growing number of molecules encoded within the major histocompatibility complex. They propose that B7 and MHC genes are derived from a common ancestor, with several members of this large gene family possibly having pivotal influences on T-cell activation. 

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