Structure and enzymology of ADP-ribosyl cyclases: conserved enzymes that produce multiple calcium mobilizing metabolites.

Abstract

Cyclic ADP-ribose is an important calcium mobilizing metabolite produced by the ADP-ribosyl cyclase (cyclases) family of enzymes. Three evolutionarily conserved ADP-ribosyl cyclase superfamily members have been identified, one from the invertebrate Aplysia californica and two from mammalian tissues, CD38 and CD157. CD38 regulates calcium signaling in a… (More)

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@article{Schuber2004StructureAE, title={Structure and enzymology of ADP-ribosyl cyclases: conserved enzymes that produce multiple calcium mobilizing metabolites.}, author={Francis Schuber and Frances E. Lund}, journal={Current molecular medicine}, year={2004}, volume={4 3}, pages={249-61} }