Structure and dynamics of sphingomyelin bilayer: insight gained through systematic comparison to phosphatidylcholine.


Sphingomyelin, one of the main lipid components of biological membranes, is actively involved in various cellular processes such as protein trafficking and signal transduction. In particular, specific lateral domains enriched in sphingomyelin and cholesterol have been proposed to play an important functional role in biomembranes, although their precise… (More)