Structure and dynamic organization of centromeres/prekinetochores in the nucleus of mammalian cells.

@article{He1996StructureAD,
  title={Structure and dynamic organization of centromeres/prekinetochores in the nucleus of mammalian cells.},
  author={Dacheng He and Bill R. Brinkley},
  journal={Journal of cell science},
  year={1996},
  volume={109 ( Pt 11)},
  pages={2693-704}
}
Although considerable research has been focused on understanding the structure and molecular organization of the centromere-kinetochore complex of mitotic chromosomes, few reports have dealt with the centromere (prekinetochore) in the interphase nucleus. In the present study, we utilized anti-centromere antibodies from the serum of patients with the autoimmune disease, scleroderma CREST (calcinosis, Raynaud's phenomenon, esophageal dismotility, sclerodactyly, telangiectasia), as probes to… CONTINUE READING
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